Open AccessInteraction of Saccharomyces boulardii With Intestinal Brush Border Membranes: Key to Probiotic Effects?
Author(s) -
Buts JeanPaul,
De Keyser Nadine
Publication year - 2010
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/mpg.0b013e3181e23271
Subject(s) - saccharomyces boulardii , probiotic , yeast , microbiology and biotechnology , brush border , medicine , saccharomyces , brush , bacteria , biology , saccharomyces cerevisiae , membrane , biochemistry , genetics , vesicle , engineering , electrical engineering
The probiotic Saccharomyces boulardii exerts beneficial effects in humans, which include trophic effects, anti‐inflammatory effects, antisecretory effects, inhibition of toxins, immunostimulatory effects, and resistance to bacterial overgrowth. This short communication discusses the interactions of the probiotic with brush border membrane (BBM) constituents because most of these effects are BBM mediated. The use of bacterial and yeast probiotics has increased dramatically in more and more clinical states, but their exact mechanisms of action remain largely unknown. The present communication focuses on the interactions of a confirmed yeast probiotic ( S boulardii) on the constituents of BBMs.