Open AccessFeasibility and Application of 3‐Dimensional Ultrasound for Measurement of Gastric Volumes in Healthy Adults and Adolescents
Author(s) -
Manini Mhd Louai,
Burton Duane D,
Meixner Duane D,
Eckert Deborah J,
Callstrom Matthew,
Schmit Grant,
ElYoussef Mounif,
Camilleri Michael
Publication year - 2009
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/mpg.0b013e318189694f
Subject(s) - medicine , interquartile range , postprandial , meal , nuclear medicine , ultrasound , radiology , insulin
Objectives: Abnormal gastric accommodation to a meal results in dyspepsia. Current methods to measure gastric volume (GV) are invasive or involve ionizing radiation. The aims of this study were t o compare fasting and postprandial (PP) GVs measured by 99m Tc‐single photon emission computed tomography (SPECT) and 3‐dimensional ultrasound (3D‐US) in adults, to assess the performance characteristics of 3D‐US measurement of GV during fasting and postprandially, and to develop normative data of GVs in 24 healthy adolescents. Patients and Methods: Eleven adults underwent SPECT and 3D‐US simultaneously to measure GV, and a second 3D‐US alone within 1 week of the first study. Twenty‐four adolescents underwent 1 3D‐US measurement. Each study included fasting, a 300‐mL Ensure meal, and 0 to 30‐minute PP GV measurements. Results: 3D‐US identifies GV accommodation to 300 mL Ensure. Delta (0–30 minutes average PP fasting) GV was 444 mL (median, interquartile range [IQR] = 422, 534) for 3D‐US and 543 mL (median, IQR = 486, 564) for SPECT ( P = 0.15). There were larger interindividual coefficients of variation for GV by 3D‐US (60.3% fasting and 21.3% average PP) compared with 19% fasting and 9.2% PP for SPECT. Intraindividual coefficients of variation for the 2 3D‐US measurements in adults were 84% fasting and 44% average PP. The estimated GVs for the adolescent group (median [25th–75th IQR]) were 33 (18–53) mL fasting, 330 (284–357) mL 30 minutes PP, and 281 (240–324) mL for delta GV. Conclusions: 3D‐US is a promising method to measure GV accommodation to a meal. Large coefficients of variation reflect the learning stage in development of this promising technique.