Open AccessSevere Abdominal Manifestations in Juvenile Dermatomyositis
Author(s) -
Besnard Caroline,
Gitiaux Cyril,
Girard Muriel,
GalmicheRolland Louise,
Talbotec Cécile,
Quartier Pierre,
Bodemer Christine,
Berteloot Laureline,
BaderMeunier Brigitte
Publication year - 2020
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/mpg.0000000000002575
Subject(s) - medicine , juvenile dermatomyositis , acute pancreatitis , refractory (planetary science) , gastroenterology , dermatomyositis , retrospective cohort study , surgery , physics , astrobiology
Juvenile dermatomyositis (JDM) is a rare and heterogeneous pediatric‐onset idiopathic inflammatory myopathy. Gastrointestinal (GI) involvement occurs in 22% to 37% of JDM patients but has only been described in case reports. In this retrospective, single‐center, observational study, we aimed to assess the causes and management of severe GI manifestations in JDM patients. We studied a cohort of 9 patients among 110 JDM patients followed during the study period (8.3%). The GI complications were related to JDM in most cases (17/19), with digestive tract involvement (n = 10), acute pancreatitis (n = 4), and hepatitis (n = 3). Three patients died from refractory JDM 2.9 years (2–3.6) after the JDM diagnosis. We highlight the need to consider pancreatitis as a main diagnostic factor in JDM patients with severe GI manifestations and the requirement of early aggressive treatment for these patients.