Open AccessComparison of Tolerance and Complication Rates Between Early and Delayed Feeding After Percutaneous Endoscopic Gastrostomy Placement in Children
Author(s) -
Peck Jacquelin,
Mills Katie,
Dey Aditi,
Nguyen Anh Thy H.,
Amankwah Ernest K.,
Wilsey Alexander,
Swan Emily,
Son Sorany,
Karjoo Sara,
McClenathan Daniel,
Wilsey Michael
Publication year - 2020
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/mpg.0000000000002503
Subject(s) - medicine , percutaneous endoscopic gastrostomy , vomiting , refeeding syndrome , nausea , gastrostomy , peg ratio , parenteral nutrition , enteral administration , early feeding , surgery , complication , pediatrics , malnutrition , finance , economics
Background: Enteral nutrition is commonly initiated 24 hours after percutaneous endoscopic gastrostomy (PEG) in children. Adult studies report safe refeeding within 1 to 6 hours of PEG, and these findings have been cautiously applied to children. Comparative studies assessing early versus next‐day refeeding in children are currently lacking. This study evaluates feeding tolerance and complications following early versus next‐day refeeding in children. Methods: This is a single‐center, pre‐post study. In June 2015 our clinical practice changed to begin refeeding within 6 hours of PEG. Children receiving early refeeding from December 2015 to August 2017 were included. A retrospective cohort from February 2013 to April 2015 was used for comparison. Results: Forty‐six children received early refeeding after PEG and 37 received next‐day refeeding. Gender distribution was similar in the 2 groups. Early refeeding patients were slightly older (3.5 vs 2.2 years) and heavier (15.5 vs 11.5 kg) at PEG placement compared to next‐day refeeding patients. Early refeeding patients experienced greater postprocedural nausea and/or vomiting (19% vs 8%, P < 0.001) and leakage, irritation, and infection around the stoma (19% vs 0.0%, P < 0.001). Compared to early refeeders, next‐day refeeding patients experienced higher occurrence of fever (35% vs 13%, P = 0.021), longer nutritional disruption (24.6 vs 3.7 hours, P < 0.001), and longer length of stay (51 vs 27 hours; P < 0.001). One next‐day refeeding patient experienced peritonitis. One early refeeding patient experienced cellulitis requiring hospitalization and a second experienced gastrostomy tube migration into the peritoneal cavity requiring removal. Conclusion: Early refeeders experienced higher rates of postprocedural nausea or vomiting and irritation, leakage, or infection around the stoma; but experienced lower rates of postoperative fever. Early refeeding resulted in reduced nutritional interruption and hospital length of stay.