Open AccessGastrointestinal Polyposis in Pediatric Patients
Author(s) -
MacFarland Suzanne P.,
Zelley Kristin,
Katona Bryson W.,
Wilkins Benjamin J.,
Brodeur Garrett M.,
Mamula Petar
Publication year - 2019
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/mpg.0000000000002421
Subject(s) - medicine , malignancy , gastrointestinal cancer , presentation (obstetrics) , genetic testing , cancer , pediatrics , colorectal cancer , intensive care medicine , general surgery , surgery
ABSTRACT Gastrointestinal polyps are mucosal overgrowths that, if unchecked, can undergo malignant transformation. Although relatively uncommon in the pediatric age group, they can be the harbingers of multiorgan cancer risk and require close management and follow‐up. Additionally, as many polyposis syndromes are inherited, appropriate genetic testing and management of relatives is vital for the health of the entire family. In this review, we discuss both common and uncommon childhood gastrointestinal polyposis syndromes in terms of clinical presentation, management, and surveillance. We also detail any additional malignancy risk and surveillance required in the pediatric age group (<21 years old). Through this review, we provide a framework for gastroenterologists to manage the multifaceted nature of pediatric polyposis syndromes.