Open AccessExperience of Using a Semielemental Formula for Home Enteral Nutrition in Children
Author(s) -
Leonard Marie,
Caldari Dominique,
Mas Emmanuel,
Lambe Cécile,
Comte Aurélie,
Ley Delphine,
Peretti Noël,
Borderon Corinne,
Marinier Evelyne,
Coste MarieEdith,
Lamireau Thierry,
Rubio Amandine,
Turquet Anne,
Dubern Béatrice,
Dabadie Alain,
Gautry Julien,
Kyheng Maeva,
Guimber Dominique,
Gottrand Frédéric
Publication year - 2019
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/mpg.0000000000002236
Subject(s) - medicine , parenteral nutrition , enteral administration , malnutrition , body mass index , pediatrics , cohort , anthropometry , cohort study , adverse effect , cross sectional study , pathology
Objectives: The use of semielemental diets concerns a small proportion of children on enteral nutrition whose characteristics have never been reported. Our aim was to describe a cohort of patients on home enteral nutrition with Peptamen Junior, including the tolerance and nutritional efficacy of this product. Methods: We performed a retrospective multicenter survey on a cohort of patients receiving this semielemental diet at home between 2010 and 2015 in 14 tertiary pediatric French centers. We recorded at baseline, 3, 6, and 12 months, and then every year the anthropometric characteristics of the patients, indications and modalities of administration of the diet, and the tolerance and adverse events. Results: We recruited 136 patients ages 9.8 ± 4.4 years at baseline. Mean body mass index z score was −1.0 ± 1.8; mean height z score was −1.1 ± 1.9. The main underlying diseases were digestive (35.3%), neurological (33.1%), and hematological (19.9%). The indications for a semielemental diet were failure of another diet in 70 patients (51.9%), severe malnutrition in 19 (14.1%), cystic fibrosis in 11 (8.1%), and switch from parenteral nutrition in 11 (8.1%). Side effects were observed in 39.2% of the patients, and required medical attention in 8.2%. Body mass index improved or remained normal in 88.3% of children. Conclusions: This semielemental diet seems to be well tolerated and efficient in the setting of home enteral nutrition in children with complex diseases featuring malabsorption and/or after failure of polymeric diet.