Open AccessCorrelation of Pancreatic Histopathologic Findings and Islet Yield in Children With Chronic Pancreatitis Undergoing Total Pancreatectomy and Islet Autotransplantation
Author(s) -
Takashi Kobayashi,
J. Carlos Manivel,
Melena D. Bellin,
Angeline M. Carlson,
Antoinette Moran,
Martin L. Freeman,
Bernhard J. Hering,
David E.R. Sutherland
Publication year - 2010
Publication title -
pancreas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.061
H-Index - 104
eISSN - 1536-4828
pISSN - 0885-3177
DOI - 10.1097/mpa.0b013e3181b8ff71
Subject(s) - medicine , islet , autotransplantation , pancreatitis , pancreatectomy , pancreas , gastroenterology , atrophy , pancreatitis, chronic , diabetes mellitus , pancreatic disease , fibrosis , pathology , endocrinology , urology , surgery , transplantation
The probability of insulin independence after intraportal islet autotransplantation (IAT) for chronic pancreatitis (CP) treated by total pancreatectomy (TP) relates to the number of islets isolated from the excised pancreas. Our goal was to correlate the islet yield with the histopathologic findings and the clinical parameters in pediatric (age, <19 years) CP patients undergoing TP-IAT.