Open AccessExpression of Epithelial-Mesenchymal Transition Markers in Treated Pancreatic Ductal Adenocarcinoma
Author(s) -
Minhua Wang,
Jeannelyn S. Estrella,
Matthew H. Katz,
Michael Kim,
Asif Rashid,
Jeffrey E. Lee,
Anirban Maitra,
Ignacio I. Wistuba,
Robert A. Wolff,
Gauri R. Varadhachary,
Huamin Wang
Publication year - 2019
Publication title -
pancreas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.061
H-Index - 104
eISSN - 1536-4828
pISSN - 0885-3177
DOI - 10.1097/mpa.0000000000001432
Subject(s) - vimentin , hazard ratio , epithelial–mesenchymal transition , oncology , immunohistochemistry , medicine , adenocarcinoma , pathology , pancreatic cancer , metastasis , confidence interval , cancer research , gastroenterology , cancer
Epithelial-mesenchymal transition (EMT) plays an important role in the progression, metastasis, and chemoresistance of pancreatic duct adenocarcinoma (PDAC); however, the expression of EMT markers and their clinical significance in PDAC patients who received neoadjuvant therapy (NAT) are unclear.