Open AccessBeyond botulinum neurotoxin A for chemodenervation of the bladder
Author(s) -
Hatim Thaker,
Sicai Zhang,
David A. Diamond,
Min Dong
Publication year - 2021
Publication title -
current opinion in urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.799
H-Index - 60
eISSN - 1473-6586
pISSN - 0963-0643
DOI - 10.1097/mou.0000000000000843
Subject(s) - medicine , overactive bladder , botulinum toxin , urology , urinary incontinence , botulinum neurotoxin , food and drug administration , urinary bladder , pharmacology , anesthesia , toxin , pathology , biochemistry , chemistry , alternative medicine
Botulinum neurotoxin A (BoNT/A), or Botox, is a popular option for overactive bladder (OAB) and neurogenic bladder (NGB) with or without incontinence. This review aims to discuss the clinical outcomes of BoNT in adult and pediatric bladder conditions, and introduces the potential benefit of novel, engineered neurotoxins beyond BoNT/A.