Open AccessClinical and biomarker assessment of frailty in liver transplantation
Author(s) -
Tumininu Ayorinde,
Guergana G. Panayotova,
Aanchal Sharma,
Keri E. Lunsford
Publication year - 2021
Publication title -
current opinion in organ transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.832
H-Index - 51
eISSN - 1531-7013
pISSN - 1087-2418
DOI - 10.1097/mot.0000000000000911
Subject(s) - medicine , cirrhosis , sarcopenia , liver transplantation , biomarker , liver disease , malnutrition , disease , intensive care medicine , transplantation , bioinformatics , biochemistry , chemistry , biology
Liver cirrhosis results in progressive decline, or frailty, which leads to poor outcomes and decreased survival. Multiple biomarkers and clinical assessment tools for quantifying frailty in liver transplant candidates exist, but a universal scoring protocol is lacking. Criteria vary between studies and correlation with patient outcome is not always clear. This review aims to summarize the pertinent biomarkers and assessment tools of frailty in cirrhosis.