Open AccessIncreased-risk donors and solid organ transplantation: current practices and opportunities for improvement
Author(s) -
Craig S. Brown,
Glenn K. Wakam,
Michael J. Englesbe
Publication year - 2020
Publication title -
current opinion in organ transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.832
H-Index - 51
eISSN - 1531-7013
pISSN - 1087-2418
DOI - 10.1097/mot.0000000000000735
Subject(s) - transplantation , medicine , intensive care medicine , risk assessment , organ transplantation , window period , disease , window of opportunity , risk of infection , immunology , biology , computer security , antibody , serology , real time computing , computer science , genetics
The development and implementation of 'increased risk donor' (IRD) status by the Centers for Disease Control (CDC) was intended to guide patients and providers in decision making regarding risk of infectious transmission via solid organ transplantation. Several contemporary studies have shown underutilization of these organs. This review summarizes the issues surrounding IRD status as well as recent advances in our understanding of the risks and benefits of increased risk organs and their appropriate utilization.