Open AccessWhen rubber meets the road: how innate features of adaptive immune cells play critical roles in transplant alloimmunity
Author(s) -
Anna B. Morris,
Mandy L. Ford
Publication year - 2019
Publication title -
current opinion in organ transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.832
H-Index - 51
eISSN - 1531-7013
pISSN - 1087-2418
DOI - 10.1097/mot.0000000000000706
Subject(s) - alloimmunity , innate immune system , immune system , acquired immune system , immunology , medicine
Studies on adaptive cells have largely focused on features that are specific to adaptive immunity. However, adaptive cells utilize innate cell features to modulate their responses, and this area of T and B-cell biology is understudied. This review will highlight recent work done to understand how innate features of adaptive immune cells modulate alloimmunity.