Open AccessBrain-related outcome measures in trials recruiting critically-ill children
Author(s) -
Ericka L. Fink,
Robert C. Tasker
Publication year - 2019
Publication title -
current opinion in pediatrics, with evaluated medline/current opinion in pediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 87
eISSN - 1080-8116
pISSN - 1040-8703
DOI - 10.1097/mop.0000000000000826
Subject(s) - medicine , intensive care medicine , randomized controlled trial , clinical trial , critically ill , medline , glycemic , surgery , pathology , political science , law , insulin , endocrinology
Randomized controlled trials leading to innovations that improve outcomes in acute life-threatening illnesses in children are scarce. A key issue is how we refocus research on outcomes that matter and are more relevant to those making emergency decisions, and those involved with managing and living with the late-outcome. We have used information from recent trials in critically ill children - in particular those illnesses without any primary neurologic involvement - to develop an approach to brain-related outcomes that will maximize child and family benefit from research.