Open AccessOsteogenesis imperfecta: advancements in genetics and treatment
Author(s) -
Vittoria Rossi,
Brendan Lee,
Ronit Marom
Publication year - 2019
Publication title -
current opinion in pediatrics, with evaluated medline/current opinion in pediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 87
eISSN - 1080-8116
pISSN - 1040-8703
DOI - 10.1097/mop.0000000000000813
Subject(s) - osteogenesis imperfecta , medicine , exome sequencing , bioinformatics , bone density conservation agents , bone density , pathology , genetics , osteoporosis , mutation , biology , gene
The purpose of this review is to outline the current understanding of the molecular mechanisms and natural history of osteogenesis imperfecta, and to describe the development of new treatments for this disorder.