Open AccessHuman hematopoiesis: aging and leukemogenic risk
Author(s) -
Emmalee R. Adelman,
María E. Figueroa
Publication year - 2020
Publication title -
current opinion in hematology/current opinion in hematology, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 97
eISSN - 1080-8213
pISSN - 1065-6251
DOI - 10.1097/moh.0000000000000622
Subject(s) - haematopoiesis , stem cell , myeloid , biology , progenitor cell , epigenetics , bone marrow , stem cell theory of aging , immunology , hematopoietic stem cell , immune system , cancer research , microbiology and biotechnology , stem cell factor , genetics , gene
Our understanding of the effects of aging on human hematopoiesis has advanced significantly in recent years, yet the full ramifications of these findings are not fully understood. This review summarizes these findings and discusses their implication as they relate to malignant hematopoiesis.