Open AccessImmunometabolism in haematopoietic stem cell transplantation and adoptive cellular therapies
Author(s) -
Erica Braverman,
Gail Waltz,
Craig A. Byersdorfer
Publication year - 2020
Publication title -
current opinion in hematology/current opinion in hematology, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 97
eISSN - 1080-8213
pISSN - 1065-6251
DOI - 10.1097/moh.0000000000000615
Subject(s) - adoptive cell transfer , cell therapy , haematopoiesis , stem cell , transplantation , immunology , immune system , cancer research , t cell , hematopoietic stem cell transplantation , medicine , biology , microbiology and biotechnology
Controlling T cell activity through metabolic manipulation has become a prominent feature in immunology and practitioners of both adoptive cellular therapy (ACT) and haematopoietic stem cell transplantation (HSCT) have utilized metabolic interventions to control T cell function. This review will survey recent metabolic research efforts in HSCT and ACT to paint a broad picture of immunometabolism and highlight advances in each area.