Open AccessThe many flavors of monocyte/macrophage--endothelial cell interactions
Author(s) -
Gloria E. Hernandez,
M. Luisa IruelaArispe
Publication year - 2020
Publication title -
current opinion in hematology/current opinion in hematology, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 97
eISSN - 1080-8213
pISSN - 1065-6251
DOI - 10.1097/moh.0000000000000573
Subject(s) - endothelium , monocyte , macrophage , adventitia , immunology , biology , progenitor cell , microbiology and biotechnology , population , cell type , stem cell , medicine , cell , anatomy , in vitro , genetics , environmental health
The well recognized plasticity and diversity, typical of monocytes and macrophages have recently been expanded by the knowledge that additional macrophage lineages originated directly from embryonic progenitors, populate and establish residency in all tissues examined so far. This review aims to summarize our current understanding on the diversity of monocyte/macrophage subtypes associated with the vasculature, their specific origins, and nature of their cross-talk with the endothelium.