Open AccessAltered functions of platelets during aging
Author(s) -
Emilie Montet,
Matthew T. Rondina,
Robert A. Campbell
Publication year - 2019
Publication title -
current opinion in hematology/current opinion in hematology, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 97
eISSN - 1080-8213
pISSN - 1065-6251
DOI - 10.1097/moh.0000000000000526
Subject(s) - platelet , platelet activation , inflammation , immunology , disease , medicine , transcriptome , biology , gene expression , gene , genetics
Platelets are specialized effector cells that rapidly respond to sites of vascular injury. However, emerging data demonstrate that platelets possess diverse functions that also mediate inflammatory responses and neurological diseases. These functions are relevant to disease processes prevalent among older adults and likely influence susceptibility to thrombotic and inflammatory disorders.