Open AccessFaecal microbiota replacement to eradicate antimicrobial resistant bacteria in the intestinal tract – a systematic review
Author(s) -
Manu P Bilsen,
Merel M C Lambregts,
Joffrey van Prehn,
Ed J. Kuijper
Publication year - 2021
Publication title -
current opinion in gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.165
H-Index - 83
eISSN - 1531-7056
pISSN - 0267-1379
DOI - 10.1097/mog.0000000000000792
Subject(s) - medicine , antibiotics , cohort , antimicrobial , intensive care medicine , carbapenem , colonisation resistance , antibiotic resistance , microbiology and biotechnology , biology
Antimicrobial resistance is a rising threat to global health and is associated with increased mortality. Intestinal colonisation with multidrug-resistant organisms (MDRO) can precede invasive infection and facilitates spread within communities and hospitals. Novel decolonisation strategies, such as faecal microbiota transplantation (FMT), are being explored. The purpose of this review is to provide an update on how the field of FMT for MDRO decolonisation has developed during the past year and to assess the efficacy of FMT for intestinal MDRO decolonisation.