Open AccessStem-cell-derived models: tools for studying role of microbiota in intestinal homeostasis and disease
Author(s) -
Rishu Dheer,
Vincent B. Young
Publication year - 2020
Publication title -
current opinion in gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.165
H-Index - 83
eISSN - 1531-7056
pISSN - 0267-1379
DOI - 10.1097/mog.0000000000000691
Subject(s) - biology , stem cell , gastrointestinal tract , organoid , microbiology and biotechnology , computational biology , function (biology) , neuroscience , biochemistry
In this review, we will summarize the recent progress made in generating stem-cell-based organoid and enteroid models of the gastrointestinal tract and their importance in understanding the role of microbes in intestinal epithelial homeostasis and disease.