Open AccessComparison of 81mKrypton and 99mTc-Technegas for ventilation single-photon emission computed tomography in severe chronic obstructive pulmonary disease
Author(s) -
Robin de Nijs,
Nienke D. Sijtsema,
Matthijs F. Kruis,
C. E. Jensen,
Martin Iversen,
Michael Perch,
Jann Mortensen
Publication year - 2020
Publication title -
nuclear medicine communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.489
H-Index - 73
eISSN - 1473-5628
pISSN - 0143-3636
DOI - 10.1097/mnm.0000000000001314
Subject(s) - copd , medicine , nuclear medicine , ventilation (architecture) , single photon emission computed tomography , pulmonary disease , lung , emission computed tomography , radiology , computed tomography , positron emission tomography , mechanical engineering , engineering
Ventilation and perfusion single-photon emission computed tomography combined with computed tomography (SPECT/CT) is a powerful tool to assess the state of the lungs in chronic obstructive pulmonary disease (COPD). 81mKrypton is a gaseous ventilation tracer and distributes similarly to air, but is not widely available and relatively expensive. 99mTc-Technegas is cheaper and has wider availability, but is an aerosol, which may deposit in hot spots as the severity of COPD increases. In this study, 81mKrypton and 99mTc-Technegas were compared quantitatively in patients with severe COPD.