Open AccessNovel approach to unpleasant symptom clusters surrounding pruritus in patients with chronic kidney disease and on dialysis therapy
Author(s) -
Rebecca S. Ahdoot,
Kamyar Kalantar-Zadeh,
James O. Burton,
Mark B. Lockwood
Publication year - 2021
Publication title -
current opinion in nephrology and hypertension/current opinion in nephrology and hypertension, with evaluated medline
Language(s) - English
Resource type - Journals
eISSN - 1080-8221
pISSN - 1062-4821
DOI - 10.1097/mnh.0000000000000752
Subject(s) - medicine , kidney disease , dialysis , quality of life (healthcare) , intensive care medicine , disease , adverse effect , anxiety , depression (economics) , nephrology , clinical practice , renal replacement therapy , physical therapy , psychiatry , nursing , economics , macroeconomics
Chronic kidney disease-associated-pruritus (CKD-aP) is a common symptom in patients with end-stage kidney disease (ESKD) undergoing dialysis. CKD-aP typically occurs alongside other debilitating symptoms and may comprise so-called 'symptom clusters' which have synergistic effects that adversely impact patient health-related quality of life (HRQoL). Importantly, symptoms in a cluster may share a common biological mechanism. Here we review the clinical impact of CKD-aP and its association with other symptoms reported by dialysis patients. The clinical benefits of treating pruritus and its potential impact on other symptoms are also addressed.