Open AccessGenetic variants of mineral metabolism in health and disease
Author(s) -
Cassianne RobinsonCohen
Publication year - 2020
Publication title -
current opinion in nephrology and hypertension/current opinion in nephrology and hypertension, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.158
H-Index - 95
eISSN - 1080-8221
pISSN - 1062-4821
DOI - 10.1097/mnh.0000000000000612
Subject(s) - genome wide association study , biology , disease , bone remodeling , bioinformatics , candidate gene , genetics , single nucleotide polymorphism , gene , medicine , genotype
Disturbances in mineral metabolism are common among individuals with chronic kidney disease and have consistently been associated with cardiovascular and bone disease. The current review aims to describe the current knowledge of the genetic aspects of mineral metabolism disturbances and to suggest directions for future studies to uncover the cause and pathogenesis of chronic kidney disease - mineral bone disorder.