Open AccessCalciprotein particles: mineral behaving badly?
Author(s) -
Edwin R. Smith,
Tim D. Hewitson,
Willi JahnenDechent
Publication year - 2020
Publication title -
current opinion in nephrology and hypertension/current opinion in nephrology and hypertension, with evaluated medline
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.158
H-Index - 95
eISSN - 1080-8221
pISSN - 1062-4821
DOI - 10.1097/mnh.0000000000000609
Subject(s) - bone mineral , chemistry , calcium , endocrinology , fibroblast growth factor 23 , medicine , bone remodeling , parathyroid hormone , osteoporosis , biology
Calciprotein particles (CPP) are formed in supersaturated solutions of calcium, phosphate and the mineral-binding protein fetuin-A. CPP have garnered considerable interest as potential mediators of mineral stress, but little consideration has been given to their origin, clearance and role in metabolism.