Open AccessMitigating risk of aldosterone in diabetic kidney disease
Author(s) -
Marie FrimodtMøller,
Frederik Persson,
Peter Rossing
Publication year - 2020
Publication title -
current opinion in nephrology and hypertension/current opinion in nephrology and hypertension, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.158
H-Index - 95
eISSN - 1080-8221
pISSN - 1062-4821
DOI - 10.1097/mnh.0000000000000557
Subject(s) - hyperkalemia , medicine , aldosterone , kidney disease , mineralocorticoid receptor , albuminuria , diabetes mellitus , kidney , endocrinology , heart failure
Diabetic kidney disease is a growing problem leading to end-stage kidney disease but also atherosclerotic cardiovascular disease and heart failure. Aldosterone is a key risk factor promoting inflammation and fibrosis causing cardio-renal failure. Current options and challenges with mitigating the risk of aldosterone are reviewed.