Open AccessAdvances in management of chronic metabolic acidosis in chronic kidney disease
Author(s) -
Wei Chen,
Matthew K. Abramowitz
Publication year - 2019
Publication title -
current opinion in nephrology and hypertension/current opinion in nephrology and hypertension, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.158
H-Index - 95
eISSN - 1080-8221
pISSN - 1062-4821
DOI - 10.1097/mnh.0000000000000524
Subject(s) - medicine , metabolic acidosis , kidney disease , acidosis , sodium bicarbonate , renal function , wasting , endocrinology , brachial artery , gastroenterology , blood pressure , chemistry
Chronic metabolic acidosis is a common complication of chronic kidney disease (CKD) and is associated with adverse consequences, such as CKD progression and muscle wasting. We review the findings from recent clinical trials that have examined the effects of sodium bicarbonate therapy and veverimer in patients with CKD and chronic metabolic acidosis.