Open AccessProtective association between JC polyoma viruria and kidney disease
Author(s) -
Jasmin Divers,
Carl D. Langefeld,
Douglas S. Lyles,
Lijun Ma,
Barry I. Freedman
Publication year - 2019
Publication title -
current opinion in nephrology and hypertension/current opinion in nephrology and hypertension, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.158
H-Index - 95
eISSN - 1080-8221
pISSN - 1062-4821
DOI - 10.1097/mnh.0000000000000464
Subject(s) - urinary system , nephropathy , immunology , focal segmental glomerulosclerosis , glomerulosclerosis , jc virus , human virome , medicine , population , kidney disease , biology , urine , kidney , virology , glomerulonephritis , progressive multifocal leukoencephalopathy , proteinuria , multiple sclerosis , gene , genetics , endocrinology , diabetes mellitus , genome , environmental health
The presence of viruses in urine (urine virome) typically reflects infection in the kidneys and urinary tract. The urinary virome is associated with HIV-associated nephropathy and chronic glomerulosclerosis. There are many associations of this microbiome with human diseases that remain to be described. This manuscript reviews emerging data on relationships between kidney disease and urinary tract infection/colonization with JC polyomavirus (JCPyV).