Open AccessGroup-based Trajectory Models to Assess Quality of INR Control and Its Association With Clinical Outcomes
Author(s) -
Aníbal GarcíaSempere,
Isabel Hurtado,
Daniel Bejarano,
Yared Santa-Ana,
Clara L. RodríguezBernal,
Salvador Peiró,
Gabriel SanfélixGimeno
Publication year - 2019
Publication title -
medical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.632
H-Index - 178
eISSN - 1537-1948
pISSN - 0025-7079
DOI - 10.1097/mlr.0000000000001253
Subject(s) - association (psychology) , trajectory , quality (philosophy) , medicine , control (management) , group (periodic table) , computer science , psychology , artificial intelligence , philosophy , chemistry , physics , organic chemistry , epistemology , astronomy , psychotherapist
The Time in Therapeutic Range (TTR) is the gold-standard measure used to assess the quality of oral anticoagulation with vitamin K antagonists. However, TTR is a static measure, and International Normalized Ratio (INR) control is a dynamic process. Group-based Trajectory Models (GBTM) can address this dynamic nature by classifying patients into different trajectories of INR control over time.