Follicular Dendritic Cell Sarcoma of the Head and Neck: Case Report and Literature Review

Objectives/Hypothesis: This article presents a case of a patient with follicular dendritic cell sarcoma (FDS), a rare neoplasm usually of the head and neck, and reviews the literature. Study Design: Literature review. Methods: A MEDLINE literature search was performed and the literature was reviewed. Results: Our patient presented with an FDS that had been excised from the upper neck and recurred in a level V node. He was treated with neck dissection and postoperative irradiation and remains disease free 5.25 years after salvage treatment. The literature search yielded 67 case reports on FDS of the head and/or neck. Most patients were treated with surgery (94%). Twenty‐eight percent of patients received adjuvant radiotherapy; 18% received adjuvant chemotherapy. Fifty percent of patients were alive with no evidence of disease at last follow‐up; 9% died from disease. Conclusions: We currently treat head and neck FDS with wide resection and postoperative radiotherapy.