Confocal Endomicroscopy Identifies Loss of Local Barrier Function in the Duodenum of Patients with Crohnʼs Disease and Ulcerative Colitis | Zendy

Guan Huei Lee | Zendy; Janina Patricia Neumann | Zendy; Torsten Hansen | Zendy; Martin Goetz | Zendy; Arthur Hoffman | Zendy; Markus F. Neurath | Zendy; Peter R. Galle | Zendy; Yiong Huak Chan | Zendy; Ralf Kießlich | Zendy; Alastair J.M. Watson | Zendy

Open Access

Confocal Endomicroscopy Identifies Loss of Local Barrier Function in the Duodenum of Patients with Crohnʼs Disease and Ulcerative Colitis

Author(s) -

Guan Huei Lee,

Janina Patricia Neumann,

Torsten Hansen,

Martin Goetz,

Arthur Hoffman,

Markus F. Neurath,

Peter R. Galle,

Yiong Huak Chan,

Ralf Kießlich,

Alastair J.M. Watson

Publication year - 2014

Publication title -

inflammatory bowel diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.932

H-Index - 146

eISSN - 1536-4844

pISSN - 1078-0998

DOI - 10.1097/mib.0000000000000027

Subject(s) - duodenum , medicine , ulcerative colitis , gastroenterology , pathology , inflammatory bowel disease , lumen (anatomy) , fluorescein , crohn's disease , disease , physics , quantum mechanics , fluorescence

Increased cell shedding with gap formation and local barrier dysfunction can be identified endomicroscopically in the terminal ileum of patients with inflammatory bowel disease. We aim to evaluate whether these changes are also present in the duodenum of patients with inflammatory bowel disease.

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