Open AccessPre-hospitalization proton pump inhibitor use and clinical outcomes in COVID-19
Author(s) -
Preethi Ramachandran,
Abhilash Perisetti,
Mahesh Gajendran,
Farla Jean-Louis,
Pardeep Bansal,
Alok Dwivedi,
Hemant Goyal
Publication year - 2021
Publication title -
european journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.881
H-Index - 102
eISSN - 1473-5687
pISSN - 0954-691X
DOI - 10.1097/meg.0000000000002013
Subject(s) - medicine , covid-19 , confounding , proton pump inhibitor , acute respiratory distress , intensive care medicine , disease , lung , pathology , outbreak , infectious disease (medical specialty)
Severe acute respiratory syndrome coronavirus-2 may escape the inactivation by gastric acid because of hypochlorhydria caused by proton pump inhibitors (PPIs), which could predispose the patients to severe COVID-19.