Open AccessUpregulation of microRNA-219-5p relieves ulcerative colitis through balancing the differentiation of Treg/Th17 cells
Author(s) -
Xinhua Li,
Lijuan Sun,
Li Chen,
Yanhao Xu,
Xinjuan Kong
Publication year - 2020
Publication title -
european journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.881
H-Index - 102
eISSN - 1473-5687
pISSN - 0954-691X
DOI - 10.1097/meg.0000000000001712
Subject(s) - downregulation and upregulation , medicine , ulcerative colitis , microrna , immunology , treg cell , colitis , pathology , il 2 receptor , gene , genetics , biology , t cell , immune system , disease
This study aimed to investigate the specific regulatory roles of microRNA-219-5p (miR-219-5p) on ulcerative colitis (UC), and reveal the potential mechanisms relating with the differentiation of Treg/Th17 cells.