Open AccessInduction of antigenic immune tolerance to delay type 1 diabetes – challenges for clinical translation
Author(s) -
Johnna D. Wesley,
Philippe P. Pagni,
Regine Bergholdt,
Frederik Flindt Kreiner,
Matthias von Herrath
Publication year - 2022
Publication title -
current opinion in endocrinology, diabetes and obesity./current opinion in endocrinology, diabetes and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.199
H-Index - 67
eISSN - 1752-2978
pISSN - 1752-296X
DOI - 10.1097/med.0000000000000742
Subject(s) - translation (biology) , immune system , immune tolerance , antigen , type 1 diabetes , medicine , immunology , diabetes mellitus , biology , genetics , endocrinology , messenger rna , gene
Dissect the field of antigen-specific immunotherapy (ASIT) in type 1 diabetes (T1D), highlighting the major barriers currently blocking clinical translation.