Open AccessPleiotropic roles of the insulin-like growth factor axis in type 1 diabetes
Author(s) -
Melanie R. Shapiro,
Mark A. Atkinson,
Todd M. Brusko
Publication year - 2019
Publication title -
current opinion in endocrinology, diabetes and obesity./current opinion in endocrinology, diabetes and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.199
H-Index - 67
eISSN - 1752-2978
pISSN - 1752-296X
DOI - 10.1097/med.0000000000000484
Subject(s) - insulin , immune system , pancreas , type 1 diabetes , endocrinology , diabetes mellitus , pancreatic islets , biology , islet , growth factor , medicine , hormone , type 2 diabetes , immunology , receptor
We review studies demonstrating lowered levels of insulin-like growth factors (IGFs) in patients with recent-onset type 1 diabetes (T1D) and discuss their potential roles in the disorder's pathogenesis.