Open AccessPeripartum cardiomyopathy and acute heart failure associated with prolonged tocolytic therapy in pregnancy
Author(s) -
Pei-Chen Li,
Huai-Ren Chang,
Sheng-Po Kao
Publication year - 2021
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000027080
Subject(s) - medicine , peripartum cardiomyopathy , heart failure , ejection fraction , pregnancy , cardiology , pulmonary edema , cardiomyopathy , postpartum period , obstetrics , lung , biology , genetics
Rationale: Peripartum cardiomyopathy (PPCM) is a rare and sometimes fatal systolic heart failure that affects women during late pregnancy or the early postpartum period. Heart failure symptoms can mimic the physiological changes of normal pregnancy, and the diagnosis is based on echocardiography. Patient concerns: A 38-year-old multiparous woman with a history of cervical incompetence underwent cervical cerclage and received tocolysis for 100 days. Diagnoses: She delivered vaginally at 37 weeks of gestation but developed postpartum decompensated acute heart failure with low left ventricular ejection fraction (LVEF: 34%) and was diagnosed with PPCM. Interventions: She received standard therapy for acute heart failure. Outcomes: The patient's pulmonary edema cleared, and she was fully ambulatory 6 days after admission. A follow-up echocardiogram 3 months later demonstrated recovery of LVEF to 66%. Lessons: Prolonged tocolysis may contribute to cardiomyopathy and should be used with caution. PPCM management requires standard treatments for acute heart failure with modifications for fetal safety.