Open AccessChinese herbal compounds containing scorpion in the treatment of epilepsy
Author(s) -
Ping Rong,
Qianfang Fu,
Xilian Zhang,
Xuan Li,
Jie Yang,
Xin Wang,
Shuai Wang,
Hui Liu,
Rong Ma,
Lianghui Nie
Publication year - 2021
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000025134
Subject(s) - medicine , epilepsy , adverse effect , population , intensive care medicine , psychiatry , environmental health
Background: Epilepsy is 1 of the common neurodevelopmental diseases. It can affect about 0.5% to 1.0% of the population regardless of their race and social class. Despite the development of a wide range of treatments, there remaining about one-third of patients still experience seizures. Chinese herbal compounds containing scorpion (CHCCS) have shown an outstanding curative effect on nerve protection and epilepsy. But there's no study to assess its clinical efficacy and safety. Methods: Each data of CHCCS in treating epilepsy from related English and Chinese databases will be searched. The primary outcome is the efficacy of the CHCCS on epilepsy. And the secondary outcomes include recurrence rate and side effects. The risk of bias will be assessed, and RevMan5.3 and Stata14.0 will be performed for meta-analysis. Finally, we will assess the level of the resulting evidence. Results: The results of the study will be combined with current evidence and published in a peer-reviewed journal. Conclusions: This study will specifically investigate the effectiveness and safety of CHCCS in treating epilepsy. INPLASY registration number: INPLASY202120056.