Open AccessA novel intubation discomfort score to predict painful unsedated colonoscopy
Author(s) -
Limei Wang,
Hui Jia,
Hui Luo,
Xiaoyu Kang,
Linhui Zhang,
Xiangping Wang,
Shaowei Yao,
Tao Qin,
Xiaomao Guo
Publication year - 2021
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000024907
Subject(s) - medicine , colonoscopy , intubation , constipation , abdominal pain , cohort , withdrawal time , surgery , anesthesia , colorectal cancer , cancer
Pain during colonoscopy is a critical quality indicator and often a limiting factor for unsedated colonoscopy. This study aimed to identify factors associated with pain during colonoscopy and establish a model for predicting a painful colonoscopy. Patients aged 18 to 80 who underwent unsedated colonoscopy were prospectively enrolled in 2 tertiary endoscopic centers in China. The primary outcome was the rate of painful colonoscopy and then we identify high-risk factors associated with painful colonoscopy. A prediction model with an intubation discomfort score (IDS) was developed and validated. Totally 607 patients participated in this study, including 345 in the training cohort and 262 in the validation cohort. Body mass index (BMI) of <18.5 kg/m 2 (OR 2.18, 95% CI: 1.09–4.37), constipation (OR 2.45, 95% CI: 1.25–4.80), and anticipating moderate or severe pain (OR 2.06, 95% CI: 1.12–3.79) were identified as independent predictive factors for painful colonoscopy and used to develop the IDS (all P < .05). Patients with IDS ≥1 had increased insertion time [9.32(6.2–13.7)] minutes vs 6.87(5.1–10.4) minutes, P = .038) and decreased cecal intubation rate (96.0% vs 99.6%, P = .044). Abdominal compression (48.4% vs 19.9%, P < .001) and position change (59.7% vs 32.1%, P < .001) were more frequently required in the group of patients with IDS ≥1. These results were externally validated in a validation cohort. The intubation discomfort score developed in this study was useful for predicting pain during colonoscopy, with IDS ≥1 indicating painful colonoscopy.