Open AccessMalignant adenomyoepithelioma of the breast
Author(s) -
Zhihao Zhang,
Yueyuan Wang,
Xiao Xie,
Jingyu Peng,
Jinghui Hong,
Lei Bi,
Ming Yang
Publication year - 2021
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000024461
Subject(s) - medicine , malignancy , mastectomy , biopsy , myoepithelial cell , physical examination , ductal carcinoma , radiology , sentinel lymph node , frozen section procedure , pathological , breast cancer , wide local excision , surgery , pathology , cancer , immunohistochemistry
Rationale: Adenomyoepithelioma (AME) is a rare biphasic tumor consisting of epithelial and Myoepithelial cell. Most of the AME is benign, and only a few will progress to malignancy, Here, we report a case of low-grade malignant adenomyoepithelioma, and review the related literature, in a bid to investigate its clinical and pathological features and thus, enhance our understanding of this tumor. Patient concerns: A 64-year-old woman visited our hospital with a 1-year history of a painless mass in her left breast. Physical examination revealed a palpable painless mass, measuring approximately 4.5 cm, in the left breast. Diagnosis: Histological examination confirmed the diagnosis of malignant adenomyoepithelioma Interventions: The patient underwent local excision of the mass, with frozen section analysis revealing ductal carcinoma in situ. Mastectomy and sentinel lymph node biopsy were then performed. Outcomes: We conducted a one-year follow-up, and relapse was not observed. Lessons: Treatment of AME remains controversial owing to the lack of high volume data and absence of prospective studies. Simple mastectomy is an acceptable treatment of this tumor.