Open AccessEfficacy and safety of Chinese medicine for obstructive sleep apnea
Author(s) -
Jun-Li Bao,
Xinyuan-Gao,
Yubo Han,
Ke Zhang,
Li Liu
Publication year - 2021
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000023903
Subject(s) - medicine , obstructive sleep apnea , epworth sleepiness scale , meta analysis , traditional chinese medicine , randomized controlled trial , data extraction , medline , sleep medicine , evidence based medicine , hypopnea , sleep apnea , physical therapy , alternative medicine , intensive care medicine , apnea , sleep disorder , polysomnography , psychiatry , pathology , cognition , political science , law
Background: Obstructive sleep apnea (OSA) is significant public concern. Clinical practice indicates that Chinese medicine has certain therapeutic advantages, while there is a lack of evidence-based medicine support. The aim of this study is to synthesize related data to explore efficacy and safety of Chinese medicine for OSA. Methods: Data in PubMed, Embase, Web of Science, CNKI, WanFang, VIP databases were comprehensively searched. All the randomized controlled trials (RCTs) in OSA children were identified, in which the effects of Chinese medicine on a range of outcomes were compared. The search had a deadline of January 1, 2020. Two investigators independently conducted data extraction and assessed the literature quality of the included studies. The Revman5.3 software was used for meta-analysis of the included literature. Results: The efficacy and safety of Chinese medicine for OSA were evaluated in terms of apnea hypopnea index (AHI, the average and lowest blood oxygen, the Epworth Sleep Scale [ESS], and adverse effects). Conclusions: This study provides reliable evidence-based support for the clinical application of Chinese medicine for OSA. PROSPERO registration number: CRD42020154864.