Open AccessPrimary pulmonary diffuse large B-cell lymphoma with multiple ground-glass nodules as the primary manifestation
Author(s) -
Qi Wang,
Yan He,
Rangrang Wang,
Chunyan Li,
Wei Li,
Yanling Xu,
Zheng Su,
Jie Zhang
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000023501
Subject(s) - medicine , lymphoma , chop , diffuse large b cell lymphoma , radiology , biopsy , lung , pathology
Primary pulmonary lymphoma (PPL) is a rare extranodal lymphoma. Only 5% to 20% of patients suffering from PPL have diffuse large β-cell lymphoma (DLBCL), and their chest computed tomography (CT) findings show single- or double-lung patchy or flocculated shadows, isolated or multifocal nodules, or masses. In this research paper, we report an older woman having multiple ground-glass nodules, who was eventually diagnosed with primary pulmonary diffuse large β-cell lymphoma (PPDLBCL). Patient concerns: A 69-year-old woman suffering from cough was admitted to the Second Hospital of Jilin University. Diagnoses: A chest CT scan showed multiple ground-glass nodules. She had received 2 weeks of antibiotic treatment, but the multiple ground-glass nodules were still present. Lung biopsy was performed by tracheoscopy, which showed non-Hodgkin diffuse large β-cell lymphoma. Interventions: The patient received R-CHOP-21 chemotherapy. Outcomes: The multiple ground-glass nodules were absorbed. Conclusion: The current study shows that spotting multiple ground-glass nodules in the lungs is a clear indication of the presence of PPDLBCL. It is important to spread awareness of PPDLBCL, which needs timely diagnosis and management.