Open AccessTen years’ disease-free survival of advanced epithelial ovarian cancer treated by cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy
Author(s) -
Jue Zhang,
LieJun Mei,
Xinghuan Wang,
Yan Li
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000023404
Subject(s) - medicine , hyperthermic intraperitoneal chemotherapy , cytoreductive surgery , ovarian cancer , chemotherapy , peritoneal cavity , surgery , carcinosis , abdominal distension , abdominal cavity , cancer , epithelial ovarian cancer , oncology , peritoneal carcinomatosis , colorectal cancer
Rationale: One of the most distinctive features of epithelial ovarian cancer is tendency to disseminate into peritoneal cavity to form peritoneal carcinomatosis, indicating advanced disease with poor prognosis. Patient concerns: A fifty-year-old patient had a chief complaint of an abdominal distension lasting 1 month. Diagnoses: The patient was diagnosed with advanced epithelial ovarian cancer with peritoneal carcinomatosis by computed tomography scan, tumor markers, endoscopy examination, and pathology. Interventions: The patient was treated with cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy followed by 8 cycles of systemic chemotherapy. Outcomes: Till March 9, 2020, the patient has disease-free survival over 10 years. Lessons: The application of cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy combined with systematic chemotherapy may improve survival dramatically for the patients with epithelial ovarian cancer and peritoneal carcinomatosis and should be considered as an option of a relatively new regime.