Open AccessTargeted temperature management in patients with severe heatstroke
Author(s) -
Yoon Seok Jung,
Hyuk-Hoon Kim,
Hee Won Yang,
Sangchun Choi
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000023159
Subject(s) - heatstroke , medicine , hypothermia , cerebral edema , organ dysfunction , targeted temperature management , hyperthermia , edema , central nervous system , anesthesia , stroke (engine) , intensive care medicine , surgery , resuscitation , return of spontaneous circulation , cardiopulmonary resuscitation , sepsis , mechanical engineering , engineering
Rationale: Unprecedented heatwaves over the past several years are getting worse with longer duration in the course of global warming. Heatstroke is a medical emergency with multiple organ involvement and life-threatening illness with a high mortality rate of up to 71%. Uncontrolled damage to the central nervous system can result in severe cerebral edema, permanent neurological sequelae, and death. However, regarding the therapeutic aspects of heat stroke, there was no therapeutic strategy after the rapid cooling of the core body temperature to <39°C to prevent further injury. Patient concerns: Each of 3 patients developed a change of mental statuses after the exposure to summer heatwaves or relatively high environmental temperatures with high humidity in the sauna. Diagnoses: The patients were diagnosed with severe heatstroke since they showed cerebral edema and multiple organ dysfunction based on the results from laboratory tests and the findings in brain computed tomography scan. Interventions: The patients underwent induced therapeutic hypothermia (<36°C) between 24 and 36 hours in the management of severe heatstroke. Outcomes: The patients survived from cerebral edema and multiple organ dysfunction. Lessons: We believe that targeted temperature management (<36°C) will help treat severe heatstroke. Thus it should be considered for reducing the chance of development of complications in multiple organs, especially in the central nervous system, when managing patients with severe heatstroke.