Open AccessThe efficacy and safety of acupoint injection for diabetic gastroparesis
Author(s) -
Ting Long,
Rensong Yue,
Tingchao Wu,
Chenyi Xu,
Maoyi Yang
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000023086
Subject(s) - medicine , medline , cochrane library , psycinfo , randomized controlled trial , data extraction , meta analysis , diabetes mellitus , intensive care medicine , clinical trial , gastroparesis , gastric emptying , stomach , political science , law , endocrinology
Background: Diabetic gastroparesis (DGP) is one of the common complications of diabetes. Accumulated evidences have shown that acupoint injection is beneficial for the clinical treatment of diabetic gastroparesis. However, there is currently no systematic review to assess this therapy. This program aims to evaluate the effectiveness and safety of this therapy for the patients with DGP. Methods and analysis: Literature search will be conducted via following electronic bibliographic databases from inception to Aug 2020: the Cochrane Library, PubMed, MEDLINE, Web of Science, EMBASE, Springer, China National Knowledge Infrastructure (CNKI), China Biology Medicine (CBM), Chinese Scientific Journal Database (VIP), Wan-Fang Database. All randomized controlled trials published in English or Chinese related to acupoint injection for DGP will be included. The primary outcome is the total effective rate. The secondary outcomes are the change of motilin and gastrin levels before and after the treatment. Two researchers will be responsible for the selection of study, extraction of data, and assessment of study quality independently. RevMan V5.3 Software will be used for assessing the risk of bias and synthesizing data. Results: This study will provide a high-quality synthesis of current available evidence for the treatment of DGP with this therapy clinically. Conclusion: The conclusions of our study will provide new evidence to judge whether acupoint injection is an effective intervention for patients suffered from DGP. OSF registration number: osf.io/ms58j.