Open AccessComparative efficacy of bariatric surgery for type 2 diabetes mellitus
Author(s) -
Xixiong Wang,
Cunren Chen,
Buping Zheng,
Xiaolong Yang,
Xiaoxin Zhang,
Chenchen Yang
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000022755
Subject(s) - medicine , checklist , meta analysis , protocol (science) , medline , type 2 diabetes mellitus , systematic review , diabetes mellitus , surgery , alternative medicine , pathology , psychology , political science , law , cognitive psychology , endocrinology
Background: The comparative efficacy of bariatric surgical procedures for type 2 diabetes mellitus (T2DM) has not been completely elucidated. To investigate this question, we conduct a systematic review and network meta-analysis. Methods: The protocol followed preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) checklist. Two review authors will independently search the PubMed, Embase (Ovid), and the Cochrane Central Register of Controlled Trials databases. The primary outcome is T2DM remission. The secondary outcomes include BMI, HbA1c (%), and percentage excess weight loss (% EWL). Results from the network meta-analysis will be presented as summary relative effect sizes (WMD or RR) and relative 95% CIs for each possible pair of treatments. Outcomes will be combined based on different periods of follow-up (12 months, 36 months, and 60 months). Results: The results will provide useful information about the efficacy of bariatric surgical procedures in patients with T2DM. Conclusion: The findings of the study will be disseminated through peer-reviewed journal. INPLASY registration number: INPLASY202050053.