Open AccessExtralobar pulmonary sequestration with elevated serum neuron-specific enolase
Author(s) -
FengWei Kong,
Weimin Wang,
Longbo Gong,
Wenbin Wu,
Miao Zhang
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000022574
Subject(s) - medicine , enolase , pulmonary sequestration , malignancy , asymptomatic , radiology , angiography , pathological , lesion , pathology , lung , immunohistochemistry
Rationale: Pulmonary sequestration (PS) presenting with elevated serum tumor markers is rare, and it might be misdiagnosed as malignancy. Patient concerns: A 26-year-old asymptomatic male patient was admitted because the x-ray showed an intrathoracic lesion. Meanwhile, the serum neuron-specific enolase (NSE) was elevated. Three-dimensional computed tomography angiography revealed an isolated feeding vessel arising from the aorta. Diagnoses: Extralobular PS was confirmed by computed tomography angiography and postoperative pathological staining. Interventions: Two-port thoracoscopic resection of the sequestrated lobe was performed. Outcomes: The serum NSE decreased to within the normal range and persisted during the follow up of 10 months. Lessons: A thorough work-up should be considered for the PS patients presenting with abnormal serum NSE. Detailed knowledge regarding the relationship between NSE and PS necessitates further studies.