Open AccessEfficacy and safety of traditional Chinese herbal formula combined with western medicine for gastroesophageal reflux disease
Author(s) -
Wuhong Lin,
Guihua Huang,
Xirong Liu,
Lin Hua-sheng,
Heng Zhou,
Chunbing Feng,
Tingshuai Wang,
Renjiu Liang
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000022454
Subject(s) - medicine , cochrane library , medline , gerd , alternative medicine , traditional chinese medicine , randomized controlled trial , traditional medicine , clinical trial , data extraction , disease , family medicine , meta analysis , intensive care medicine , reflux , pathology , political science , law
Background: The combined therapy of Chinese herbal formula and western medicine against gastroesophageal reflux disease (GERD) could significantly improve the clinical effect, reduce the recurrence rate and the side effects of western medicine, and even reduce the dosage and course of treatment of western medicine. This study tried to systematically evaluate the efficacy and safety traditional Chinese herbal formula combined with western medicine in the treatment of GERD. Methods: Randomized controlled trials of traditional Chinese herbal formula combined with western medicine for GERD patients will be systematically searched using the PubMed, Embase, Medline, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang database, Chongqing VIP Chinese Science and Technology Periodical Database, and Chinese Biological and Medical database (CMB) until Aug. 28, 2020. Two researchers will perform data extraction and risk of bias assessment independently. Statistical analysis will be conducted in RevMan 5.3. Results: This study will summarize the present evidence by exploring the efficacy and safety of traditional Chinese herbal formula combined with western medicine in the treatment of GERD. Conclusions: The findings of the study will help to determine potential benefits of traditional Chinese herbal formula combined with western medicine against GERD. Ethics and dissemination: The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences. OSF Registration number: DOI 10.17605/OSF.IO/RSAVF.