Open AccessCoronavirus disease 2019-associated rapidly progressive organizing pneumonia with fibrotic feature
Author(s) -
Satoshi Okamori,
Ho Lee,
Yasushi Kondo,
Yasushi Akiyama,
Hiroki Kabata,
Yuko Kaneko,
Makoto Ishii,
Naoki Hasegawa,
Koichi Fukunaga
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000021804
Subject(s) - medicine , bronchiectasis , pneumonia , halo sign , cryptogenic organizing pneumonia , lung , covid-19 , respiratory system , pulmonary fibrosis , viral pneumonia , coronavirus , respiratory disease , fibrosis , disease , radiology , infectious disease (medical specialty)
Pneumonia is one of the most important characteristics of coronavirus disease 2019 (COVID-19) and imaging findings of COVID-19 pneumonia are diverse and change over disease course. However, the detailed clinical course of organizing pneumonia (OP) caused by COVID-19 has not been clarified. Patient concerns: A 60-year-old man and a 61-year-old woman diagnosed with mild COVID-19 were admitted to our hospital. Their respiratory symptoms were deteriorating even after initiating treatment with antiviral drugs. Diagnosis: Chest X-rays and computed tomography scan showed a rapid progression of linear consolidation with reversed halo sign, distributed in subpleural and peri-bronchial regions. They also presented with pulmonary fibrosis findings, including traction bronchiectasis and marked lung volume reduction. They were diagnosed with rapidly progressing OP. Interventions: They were treated with systemic corticosteroids. Outcomes: The patients’ imaging findings and respiratory conditions improved rapidly without any adverse effects. Conclusion: Physicians should carefully monitor patients with COVID-19, as they can develop rapidly progressive and fibrotic OP, which respond to corticosteroids.