Open AccessThe Control and Prevention of COVID-19 Transmission in Children
Author(s) -
Gidyenne Christine Bandeira Silva de Medeiros,
Ana Clara de França Nunes,
Kesley Pablo Morais de Azevedo,
Victor Hugo de Oliveira Segundo,
Gilberto Martins Santos,
Ádala Nayana de Sousa Mata,
Isac Davidson Santiago Fernandes Pimenta,
Isaac Newton Machado Bezerra,
Liliane Pereira Braga,
Helaine Carneiro Capucho,
Márcia Regina Piuvezam,
Valter Cordeiro Barbosa Filho,
José Carlos Leitão,
Daniel Guillén Martínez,
Grasiela Piuvezam
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000021393
Subject(s) - medicine , covid-19 , transmission (telecommunications) , betacoronavirus , coronavirus infections , medline , pandemic , virology , outbreak , disease , telecommunications , political science , law , computer science , infectious disease (medical specialty)
Background: The pandemic following the rapid spread of the new SARS-CoV-2 virus has hit all continents and caused thousands of deaths worldwide. Evidence has been published on epidemiological and clinical characteristics of population groups considered at risk; however, information for the other population groups, especially for the child population, is needed. In this context, this protocol describes a systematic review that will aim to identify the evidence on control and prevention of COVID-19 transmission among children and adolescents, as well as to describe the epidemiological profile and clinical and immunological characteristics of COVID-19 in this population. Methods: This protocol will be developed in accordance with PRISMA-P. The searches will be conducted in PubMed, Web of Science, ScienceDirect, EMBASE, and Scopus, seeking clinical trials. Observational studies and case reports with Children and adolescents (≤19 years) infected with SARS-CoV-2 will be included whether they report information on the control of prevention and COVID-19 transmission. Two independent researchers will perform the selection of articles, removal of duplication, and screening by Rayyan QCRI application. Cochrane's RoB 2.0, ROBINS-I, and CASP tools will be used to assess the risk of bias. Meta-analysis, subgroup analyses, and/or descriptive analyses will be carried out based on the data conditions included. Results: A high-quality synthesis of the available evidences on the epidemiological profile, the clinical and immunological characteristics involved in children, and adolescents diagnosed with COVID-19, as well as the participation of this population in the transmission dynamics of SARS-CoV-2 will be provided. Conclusion: This systematic review has an important relevance in the current context because it has a great potential to help the development of new control and prevention strategies in the pediatric population. Record of systematic review: CRD42020179263.