Open AccessTailgut cyst with adenocarcinoma transition
Author(s) -
Min Wang,
Guoliang Liu,
Yu Mu,
Hong He,
Shuang Wang,
Jiannan Li
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000020941
Subject(s) - medicine , histopathology , carcinoembryonic antigen , cyst , magnetic resonance imaging , adenocarcinoma , radiology , pathology , cancer
Rationale: Tailgut cyst (TGC) is a rare congenital disease that originates from residues of the tail intestine during the embryonic period. Most TGCs are benign lesions and the malignant transition is very rare. Patient concerns: A 50-year-old woman attended our department complaining of defecation difficulty for more than 2 months. She reported irregular defecation with a small amount of liquid stool, 3 to 4 times per day. Diagnosis: Biochemical analysis showed high levels of carcinoembryonic antigen (79.89 ng/mL; normal, 0–3 ng/mL) and carbohydrate antigen 199 (57.60 U/mL; normal, 0–35 U/mL). Abdominal computer tomography and magnetic resonance imaging showed a large cystic mass with enhanced signals. Post-surgical histopathology indicated that the mass was a TGC with adenocarcinoma transition. Interventions: The cyst was completely resected. Symptomatic treatment was further performed, and the patient recovered well. Lessons: We reported a rare case of a large TGC with adenocarcinoma transition. CT, MRI, and histopathology are important to diagnose TGC. Complete surgical resection is the first choice to treat TGC.