Open AccessNon-pharmaceutical therapy for post-stroke shoulder-hand syndrome
Author(s) -
Qiang Gao,
Huaili Nie,
Chunyan Zhu,
Naifeng Kuang,
Xiaoyu Wang,
Yiqian Chen,
Xiao Zhang,
Dewen Zheng,
Qing Xia,
Tao Yin,
Limin Pan,
Liangzhen Xie
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000020527
Subject(s) - medicine , stroke (engine) , randomized controlled trial , meta analysis , grading (engineering) , medline , physical therapy , clinical trial , evidence based medicine , alternative medicine , intensive care medicine , surgery , mechanical engineering , civil engineering , pathology , political science , law , engineering
Background: Shoulder-hand syndrome (SHS) is a common complication in post-stroke patients. SHS has a large impact on patients and their families, communities, healthcare systems and businesses throughout the world. Non-pharmaceutical therapy for post-stroke SHS is the most common treatment in clinical practice, but their effectiveness is still unclear. The aim of this study is to assess the effect and safety of non-pharmaceutical therapeutic strategies for post-stroke SHS. Method: We will search 3 in English and 4 in Chinese languages electronic databases regardless of publication date or language. We will include randomized controlled trials (RCTs) assessing the effect of any non-pharmaceutical therapy for post-stroke SHS. Primary outcomes will be any effective instrument for post-stroke SHS. Two authors will independently assess the risk of bias by using Cochrane tool of risk of bias. We will perform network meta-analysis in random effects model to estimate the indirect and mixed effects of different therapeutic strategies by R-3.5.1 software. We will assess the confidence in cumulative evidence by Grading of Recommendations Assessment, Development and Evaluation. Results: This study will be to assess the effect and safety of non-pharmaceutical therapy for post-stroke SHS. Conclusions: This study will assess the effect of different non-pharmaceutical therapeutic strategies for post-stroke SHS and provide reliable evidence for the choice of treatments. Systematic review registration: PROSPERO (CRD42019139993).